Morphometric variability of neuroimaging features in Children with Agenesis of the Corpus Callosum

Morphometric variability of neuroimaging features in Children with Agenesis of the Corpus Callosum

BACKGROUND Agenesis of the corpus callosum (ACC) is a developmental brain malformation associated with a wide spectrum of structural brain abnormalities and genetic loci. To characterize the diverse callosal morphologies and malformations of brain development associated with ACC, we report on the neuroimaging findings of 201 individuals diagnosed with corpus callosal abnormalities. METHODS We...

Neurodevelopmental Outcome of Patients With Agenesis of Corpus Callosum

Background: Agenesis of Corpus Callosum (ACC) is a type of brain dysgenesis with various clinical manifestations. Objectives: This study aimed to investigate the clinical and neurodevelopmental outcomes of patients with ACC. Materials & Methods: In this cross-sectional study, the clinical and neurodevelopmental conditions of 62 patients with complete ACC referred to subspecialty clinics of pe...

Agenesis of the Corpus Callosum with Rare Dysmorphic Features

Agenesis of corpus callosum is a common congenital or developmental malformation of brain. This is a case report of 13 year old female presented with delayed milestones, mental retardation, refractory hypertension and pallor since childhood. She had dysmorphic facies in the form of thick eyebrows, hypertelorism, low anterior hairline, hirsuitism, broad nose, thickened lips and low set ears. Upp...

Agenesis of the Corpus Callosum

Agenesis of the Corpus Callosum

COMPLETE or partial agenesis of the corpus callosum is uncommon especially in adults; the incidence amongst patients in institutions where numerous air encephalograms are performed is 3% (Carpenter and Drukemiller, 1953). Reil (1812) published the first report of a case, describing the necropsy findings in a 30 year old woman of low mentality; further cases discovered at necropsy were subsequen...